Scholarship: Full scholarship (Salary will be strictly in line with NIH standards.)
Degree: PhD, MD
Nationality: International Students
Application deadlines: Open
Research in Dr Deqiang Li’s laboratory focuses on understanding the mechanisms of cardiovascular development, disease and regeneration. The laboratory is working to identify epigenetic regulation and novel signalling pathways that regulate myocardial development or control cardiomyocyte differentiation and maturation using in vitro and in vivo approaches. Cellular and mouse model systems are used in specific research projects, including induced pluripotent stem cells (iPSCs) and conditional gene knockouts. Various cutting-edge biomedical technologies have also been employed, including CRISPR/Cas9 genome editing, AAV, single-cell RNA-Seq and ChIP-Seq, confocal microscopy, multicolour flow sorting, surgical construction of disease models, ultrasound and telemetry to measure cardiovascular function in mice. For more details, see our recent papers in JCI (PMID:29337306) and Circ Res (PMID:35722872).
The Ohio State University is ranked 32nd in U.S. News and World Report’s 2021 “Best Medical Schools: Primary Care’ and 30th in ‘Best Medical Schools: Scientific Research”. The affiliated National Children’s Hospital (NCH) is nationally ranked in all 10 pediatric specialties by U.S. News and World Report, and was ranked the 8th best children’s hospital in the U.S. for 2020-2021 by U.S. In addition, NCH has an outstanding group of scientists in cardiovascular research, particularly in cardiovascular cell signalling, development and regeneration. NCH values diversity and encourages candidates from diverse backgrounds to apply and participate in a variety of research projects.
- Understanding of mechanisms of cardiovascular development, disease and regeneration
- Proven skills and experience in molecular biology, mouse genetics or the construction of surgical models of the mouse heart;
- A strong work ethic and a keen interest in cardiovascular development and regeneration;
- In addition, good written and oral communication skills in English and the ability to work independently on projects and collaborate in research;
- Preference will be given to candidates with a background and experience in developmental biology using mouse models, iPSC or cardiac surgery mouse models.
Interested students are invited to send their CV to [email protected].