Nationality: International Students
Application deadlines: Open
The overarching research focus of the S. Zhang Lab is to investigate the cancer-driving mechanisms that reside in the dynamic and evolutionary nature of the primary tumor microenvironment and metastatic niche. Our lab seeks to delineate patterns of metastatic plasticity and identify targetable mechanisms for novel cancer therapeutics. For more information, please refer to the lab website (https://www.curiosityrover.org) and our recent publications (Cell 2020 Nov 25;183(5):1234-1248.e25. doi: 10.1016/j.cell.2020.09.064and Nat Commun. 2020 Jun 15;11(1):3017. doi: 10.1038/s41467-020-16832-2.).
The prospective candidate will have ample freedom to collaboratively develop research projects with Dr. Zhang under the above overarching theme. The postdoctoral training will involve utilizing single cell genomics and functional genomics approaches – coupled with cellular, organotypic, and mouse models of cancer – to reveal novel molecular mechanisms that drive tumor progression, drug resistance, and metastatic relapse.
UT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. As an equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis of race, color, religion, national origin, sex, sexual orientation, gender identity, gender expression, age, disability, genetic information, citizenship status, or veteran status.
- To study cancer cell signaling, metastasis, tumor microenvironment, and tumor immunology using cutting-edge functional genomics and single-cell omics approaches.
- Candidates must hold a recent Ph.D. and/or M.D. degree. Experience in cell biology, cancer biology, genetics, immunology, or a similar field.
- Experience in mouse models, spectral flow cytometry, specialized sequencing (CITE-, TCR-, ATAC-single cell), multi-omics approaches, and/or bioinformatics (Python, R) will be favorably reviewed.
Interested individuals should send a CV, statement of interests, and a list of three references to:
Dr. Siyuan Zhang
Department of Pathology
ND6.200A, T. Boone Pickens Biomedical Building (ND)
Simmons Comprehensive Cancer Center
The University of Texas Southwestern Medical Center
6001 Forest Park Rd, Dallas, TX 75235
Phone: 214-648-6537 (Office) 214-648-6539 (Lab)
Email: [email protected]
Lab URL: https://www.curiosityrover.org